| 1990 - 1996 | coordinator of the Munich research program "Morbus Parkinson and other basal ganglia disorders", supported by the German ministry of education and research |
| 1999 - 2007 | coordinator of the German medical competence Network „Parkinson Syndrome“, supported by the German ministry of education and research (22 universities and 22 specialised Parkinson clinics participating) |
| since 2000 | member, board of directors of the coordination centre for clinical studies (KKS), Marburg, supported by the German ministry of education and research (BMBF) |
| 2001 - 2002 | coordinator of the national Remote-Data-Entry-internet based patient registry ‘restless legs syndrome’, supported by the German ministry (BMBF), coordinated by the Dep. Neurology, University Marburg (7 Universities participating) |
| 2001 - 2004 | coordinator of the European network of research, diagnosis and therapy in Parkinson’s disease (EuroPa), supported by the European Community, coordinated by the Dep. Neurology, University Marburg (11 European countries participating) |
| since 2003 | Chairman of the German Parkinson Study Group (GPS) of the Competence Network on Parkinson's Disease |
Organisation of study groups and meetings
Organizer and member of the organisation committees of more than 50 national and international congresses, conferences, meetings and study program meetings
Experience with clinical trials
| since 1996 | Principal Investigator for more than 20 clinical trials Investigator for more than 40 clinical trials Experience in planing and performing Investigator Initiated Trials Experience in performing national and international Multicenter Trials due to ICH-GCP for patients with Parkinson´s Disease, patients with Atypical Parkinsonian Syndromes, patients with Parkinson´s Disease Dementia and patients with Restless Legs Syndrome |
Main research
Parkinson disease and atypical Parkinson syndromes: neurodegeneration, diagnosis, neuroimaging, pharmacotherapy, stem cell-research, animal models for neurodegenerative disease; other basalganglia disorders (Wilson’s disease, Chorea Huntington); neurological sleep disorder (REM sleep behaviour disorder narcolepsy, restless legs syndrome); dementia (Alzheimer’s disease, dementia with Lewy bodies)